TNF antagonist drugs for Crohn’s disease


Oct 18, 2012
Crohn’s disease and ulcerative colitis treatments are no longer restricted to fewer number of medications and surgical procedures. With the current advancements, and invention of specialized surgical methods, Crohn’s disease and ulcerative colitis therapies have underwent significant transformations. Apart from chemically-derived drugs like TNF antagonist medications, inflammatory bowel diseases can be combated effectively with the aid of biologic agents that help curb the disease conditions without suppressing the immune system as a whole. Biologic agents target the pro-inflammatory proteins and subsequently neutralize them, thus curbing IBD-related inflammation, which often worsens the health condition of the patients. Medications like monoclonal antibodies can help curb TNF alpha effectively, thus managing Crohn’s disease conditions effectively, before they deteriorate to the worst phases where medications no longer help achieve remission or the symptom-free phase. Both biologics and chemically obtained drugs help relieve Crohn’s disease and keep patients in remission. However, biologics are recommended only during the latter part of the treatment process, while the chemically-derived medications like corticosteroids are included in the preliminary phase, in order to quickly curb Crohn’s disease conditions, before the start deteriorating. Patients who suffer from moderate to severe stages of Crohn’s disease, and fail to respond to chemically-derived drugs, have to start consuming biologics, as they help ease the risks of the disease conditions. The most widely used and FDA approved biologics for Crohn’s are: Cimzia Humira Remicade Tysabri While the advantages that biologics drugs promise are immense, they also contain the respective medical warnings that indicate the possible side effects to be careful about. For example, if a Crohn’s disease patient continues to experience serious infections while consuming biologics, the drug should be discontinued soon, to avert life-threatening impacts. Moreover, patients who suffer from multiple sclerosis, tuberculosis, and heart failure should avoid biologic agents, as they might worsen the disease conditions. More information can be obtained on a bespoke social networking website, developed solely for gastroenterologists around the world. GI health care experts who specialize in GI disorders can register with The Gut People and start interacting with top GI experts around the world, on various commonly found gastrointestinal disorders like inflammatory bowel disease and intestinal tuberculosis. The Gut People is also equipped with unique functionalities that help download informative documents on gastrointestinal disorders, as well as their comprehensive diagnosis steps and advance treatment methods. For more info: